barbecue beef sandwich with a side of potato salad on a white plate that is sitting on a red and white check napkin
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Slow Cooker Barbecue Beef Sandwiches

These Tangy & Sassy Slow Cooker Barbecue Beef Sandwiches are the perfect solution for those busy weeknight meals!
Prep Time10 mins
Cook Time7 hrs
Total Time7 hrs 10 mins
Course: Main Course
Cuisine: American
Keyword: beef, barbecue, sauce, spice, rub, recipe, sandwich, slow cooker
Servings: 12 Servings
Calories: 369kcal
Author: Lisa Johnson


Spice Rub

  • 1/2 Tablespoon chili powder
  • 1/2 Tablespoon garlic powder
  • 1/2 Tablespoon onion powder
  • 1/2 Tablespoon brown sugar
  • 3 pound beef chuck roast trimmed
  • 1 cup barbecue sauce*
  • 12 hamburger buns


  • Mix spice rub ingredients together in a small bowl, set aside.
  • Sprinkle spice rub over all sides of the beef chuck roast.
  • Place roast in slow cooker, and cook on HIGH for 6 hours or LOW for 8 hours.
  • Shred beef with two forks and return to the slow cooker.
  • Mix in the barbecue sauce and cook for an additional 30 to 60 minutes.
  • Store left over barbecue beef in the refrigerator for up to a week.



Calories: 369kcal | Carbohydrates: 32g | Protein: 26g | Fat: 14g | Saturated Fat: 6g | Cholesterol: 78mg | Sodium: 557mg | Potassium: 496mg | Fiber: 1g | Sugar: 11g | Vitamin A: 165IU | Vitamin C: 0.7mg | Calcium: 104mg | Iron: 4.1mg